These are publications from work undertaken by Frontier Science (Scotland).

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John F R Robertson;  A Di Leo; S Johnston; S Chia; J M Bliss; R J Paridaens; J Lichfield; I Bradbury; C Campbell;  12-FEB-2021

Meta-analyses of visceral versus non-visceral metastatic hormone receptor-positive breast cancer treated by endocrine monotherapies

npj Breast Cancer,  7,11, doi:10.1038/s41523-021-00222-y

John F R Robertson;  R J Paridaens; J Lichfield; I Bradbury; C Campbell;  05-JAN-2021

Meta-analyses of phase 3 randomised controlled trials of third generation aromatase inhibitors versus tamoxifen as first-line endocrine therapy in postmenopausal women with hormone receptor-positive advanced breast cancer

European Journal of Cancer,  Volume 145, Pages 19-28, doi:10.1016/j.ejca.2020.11.038

J Bines;  E Clark; C Barton; E Restuccia; M Procter; A Sonnenblick; D Fumagalli; D Parlier; A Arahmani; J Baselga; G Viale; L Reaby; E Frank; RD Gelber; M Piccart; C Jackisch; JA Petersen;  April 2021

Patient-reported function, health-related quality of life, and symptoms in APHINITY: pertuzumab plus trastuzumab and chemotherapy in HER2-positive early breast cancer

British Journal of Cancer,  Jul 125(1), pp 38-47 (2021) doi:10.1038/s41416-021-01323-y

S Martel;  M Lambertini; D Agbor-Tarh; N Ponde; A Gombos; V Paterson; F Hilbers; LA Korde; A Manukyants; A Dueck; C Maurer; M Piccart; A Moreno-Aspitia; C Desmedt; S Di Cosimo; E. de Azambuja;  January 2021

Body Mass Index and Weight Change in Patients With HER2-Positive Early Breast Cancer: Exploratory Analysis of the ALTTO BIG 2-06 Trial

Volume 19, Issue 2, 05 January 2021 doi:10.6004/jnccn.2020.7606

A Sonnenblick;  D Agbor-Tarh; E. de Azambuja; S Hultsch; M Izquierdo; M Liu; G Pruneri; N Harbeck; M Piccart; A Moreno-Aspitia; R Zvi Granit; G Rouas; I Fahoum; C Sotiriou;  November 2020

STAT3 activation in HER2-positive breast cancers: Analysis of data from a large prospective trial

International Journal of Cancer,  05 November 2020 doi:10.1002/ijc.33385

M Lambertini;  D Agbor-Tarh; O Metzger-Filho; N Ponde; F Poggio; F Hilbers; LA Korde; S Chumsri; O Werner; L del Mastro; R Caparica; V Moebus; A Moreno-Aspitia; M Piccart; E. de Azambuja;  January 2020

Prognostic role of distant disease-free interval from completion of adjuvant trastuzumab in HER2-positive early breast cancer: analysis from the ALTTO (BIG 2-06) trial

ESMO Open,  Volume 5, Issue 6 doi:10.1136/esmoopen-2020-000979

S Di Cosimo;  L Porcu; D Agbor-Tarh; S Cinieri; MA Franzoi; MC De Santis; C Saura; J Huober; D Fumagalli; M Izquierdo; M Piccart; MG Daidone; E. de Azambuja;  October 2020

Effect of body mass index on response to neo-adjuvant therapy in HER2-positive breast cancer: an exploratory analysis of the NeoALTTO trial

Breast Cancer Research,  22, Article Number 115 (2020) doi:10.1186/s13058-020-01356-w

ANJ Tutt;  JE Garber; B Kaufman; G Viale; D Fumagalli; P Rastogi; RD Gelber; M E de Azambuja; A Fielding; J Balmaña; SM Domchek; K Gelmon; SJ Hollingsworth; LA Korde; B Linderholm; H Bandos; E Senkus; JM Suga; Z Shao; AW Pippas; Z Nowecki; T Huzarski; PA Ganz; PC Lucas; N Baker; S Loibl; R McConnell; M Piccart; R Schmutzler; GG Steger; JP Costantino; A Arahmani; N Wolmark; E McFadden; V Karantza; SR Lakhani; G Yothers; C Campbell; CE Geyer Jr;  2021

Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer

The New England Journal of Medicine,  Published online June 03, 2021, doi:10.1056/NEJMoa2105215

M Piccart;  M Procter; D Fumagalli; E. de Azambuja; E Clark; M S Ewer; E Restuccia; G Jerusalem; S Dent; L Reaby; H Bonnefoi; I Krop; T-W Liu; T Pie?kowski; M Toi; N Wilcken; M Andersson; Y H Im; L M Tseng; H-J Lueck; M Colleoni; E Monturus; M Sicoe; S Guillaume; J Bines; RD Gelber; G Viale; C Thomssen;  2021

Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer in the APHINITY Trial: 6 Years’ Follow-Up

Journal of Clinical Oncology,  Published online February 04, 2021, doi:10.1200/JCO.20.01204

E Riley;  E McFadden;  2020

Contracts and Budgets

In: Piantadosi S., Meinert C.L. (eds) Principles and Practice of Clinical Trials,  Published online November 23 2020, doi:10.1007/978-3-319-52677-5_47-1>,