FSS | PUBLICATIONS
PUBLICATIONS
Explore articles based on work undertaken by Frontier Science Scotland
ALEXANDRA | Journal of the American Medical Association (JAMA)
The addition of the immune therapy drug atezolizumab to chemotherapy after surgery did not provide benefit among patients with triple-negative breast cancer who are at high risk of recurrent disease.
ALTTO | ESMO Open
Final 10-year analysis of the ALTTO trial exploring dual anti-HER2 blockade with lapatinib + trastuzumab compared to trastuzumab alone.
APHINITY | Journal of Clinical Oncology
Adjuvant Pertuzumab and Trastuzumab in Early Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer in the APHINITY Trial: Third Interim Overall Survival Analysis With Efficacy Update
OlympiA results in the subset of patients from Japan
The consistency of results between the subset of patients from Japan and the global OlympiA population supports the clinical benefit of adjuvant olaparib for patients with gBRCA1/2pv and HER2-negative, high-risk eBC in Japan after completion of local treatment and neoadjuvant or adjuvant CT.
Cardiac Safety in the APHINITY trial
ESMO Open has published an article confirming the cardiac safety of adjuvant anti-HER2 treatment with pertuzumab and trastuzumab.
NeoALTTO: European Journal of Cancer (EJC)
Ten-year survival of neoadjuvant dual HER2 blockade in patients with HER2-positive breast cancer
Overall survival in the OlympiA trial
OlympiA demonstrates statistically significant improvement in overall survival with adjuvant olaparib compared with placebo
APHINITY | Annals of Oncology
Adjuvant pertuzumab and trastuzumab in patients with early HER-2 positive breast cancer in APHINITY: 8.4 years’ follow-up
OlympiA | ESMO Virtual Plenary Abstract | Annals of Oncology
Pre-specified event driven analysis of Overall Survival (OS) in the OlympiA phase III trial of adjuvant olaparib (OL) in germline BRCA1/2 mutation (gBRCAm) associated breast cancer